Implication of Ultraviolet Irradiation in Photo-carcinogenesis

Résumé

Human skin is exposed, on a daily basis, to various exogenous threats including ultra violet (UV) solar rays. Long-term UV exposure can lead to serious consequences such as photo ageing, freckles as well as formation of either malignant or benign skin tumors. Such exposure activates distinct signaling pathways and triggers the formation of lesions whose regulation and repair are fine-tuned and can determine the cell’s fate (survival, apoptosis or carcinogenesis).