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Cette section regroupe les recherches en médecine et pharmacie menées par le BGE et le TIMC dans le cadre du projet. Les publications traitent principalement des mécanismes biologiques sous-jacents de la peau, tels que l'impact des rayonnements ultraviolets, les processus de réparation de l'ADN et les voies de signalisation impliquées dans les cancers de cet organe.


A. Nasrallah, H.R. Rezvani, F. Kobaisi, A. Hammoud, J. Rambert, J.P.H. Smits, E. Sulpice, W. Rachidi, Generation and characterization of CRISPR-Cas9-mediated XPC gene knockout in human skin cells, 14(1):30879, 2024

F. Kobaisi, E. Sulpice, A. Nasrallah, et al, Synthetic rescue of Xeroderma Pigmentosum C phenotype via PIK3C3 downregulation, Cell Death Dis 15, 847, 2024

Paul-Traversaz Manon, Umehara Kaoru, Watanabe Kenji, Rachidi Walid, Sève Michel, Souard Florence, Kampo herbal ointments for skin wound healing, Frontiers in Pharmacology, Volume 14, 2023

M. Fayyad-Kazan, F. Kobaisi, A. Nasrallah, P. Matarrese, R. Fitoussi, S. Bourgoin-Voillard, M. Seve, W. Rachidi, Effect of Ultraviolet Radiation and Benzo[a]pyrene Co-Exposure on Skin Biology: Autophagy as a Potential Target, Int J Mol Sci, 2023

A. Nasrallah, E. Sulpice, F. Kobaisi, X. Gidrol, W. Rachidi, CRISPR-Cas9 Technology for the Creation of Biological Avatars Capable of Modeling and Treating Pathologies: From Discovery to the Latest Improvements, Cells, 2022

A. Nasrallah, N. Fayyad, F. Kobaisi, B. Badran, H. Fayyad-Kazan, M. Fayyad-Kazan, M. Sève, W. Rachidi, Xeroderma Pigmentosum C: A Valuable Tool to Decipher the Signaling Pathways in Skin Cancers, Oxidative Medicine and Cellular Longevity, 2021, 6689403, 14 pages, 2021

F. Kobaisi , N. Fayyad , HR. Rezvani , M. Fayyad-Kazan , E. Sulpice , B. Badran , H. Fayyad-Kazan , X. Gidrol , W. Rachidi, Signaling Pathways, Chemical and Biological Modulators of Nucleotide Excision Repair: The Faithful Shield against UV Genotoxicity, Oxid Med Cell Longev, 2019 

F. Kobaisi, E. Sulpice, M. Fayyad-Kazan, A. Nasrallah, X. Gidrol, H. Fayyad-Kazan, W. Rachidi, Implication of Ultraviolet Irradiation in Photo-carcinogenesis, In: Hussein Fayyad Kazan, editor. Immunology and Cancer Biology, Hyderabad, India: Vide Leaf, 2021

N. Fayyad, F. Kobaisi, M. Fayyad-Kazan, A. Nasrallah, H. Fayyad-Kazan, W. Rachidi, Link between Base Excision Repair (BER), Reactive Oxygen Species (ROS), and Cancer, In: Hussein Fayyad Kazan, editor. Immunology and Cancer Biology. Hyderabad, India: Vide Leaf. 2021

Publié le 24 mars 2025

Mis à jour le 25 mars 2025